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The annals of pharmacotherapy skip to main page content home current issue archives contact us subscriptions alerts help site map quick search author: keyword: year: vol: page: go [advanced search] [browse the archive] user name password sign in case report treatment of pediatric idiopathic pulmonary hemosiderosis with low-dose cyclophosphamide shiou-huei huang , msc pediatric critical care pharmacist, department of pharmacy, chang-gung memorial hospital, kaohsiung, taiwan ping-yu lee , msc director, department of pharmacy, chang-gung memorial hospital chen-kuang niu , md chief, division of pediatric pulmonology, chang-gung children's hospital, kaohsiung reprints: chen-kuang niu md, division of pediatric pulmonology, chang-gung children's hospital, no. Viagra buy phone 123, dabi rd. , niausung shiang, 833, kaohsiung, taiwan, fax 886 7 7338009, niusnet{at}ms10. buy viagra online in usa Hinet. Buy generic viagra without prescription Net abstract objective: to report the safety and efficacy of long-term, low-dose cyclophosphamide therapy in a child with idiopathic pulmonary hemosiderosis (iph). Case summary: a 7-year-old boy diagnosed with iph 4 years previously was initially prescribed prednisolone. buy cheap viagra canada Because he only had a transient response to prednisolone, oral cyclophosphamide 2 mg/kg/d was later added. Buy viagra canada A dramatic improvement was noted during the subsequent follow-up. buy viagra online in the united states One year after cyclophosphamide therapy, the patient suddenly developed thrombocytopenia (platelet count 75 ã— 10 3 /mm 3 ), with the platelet count decreasing to 10 ã— 10 3 /mm 3 over the following 10 months. where to buy generic viagra Cyclophosphamide was tapered to an alternating daily dosage of 1 mg/kg. The tapering resulted in a subsequent increase in the platelet count, which was maintained between 20 and 50 ã— 10 3 /mm 3 without occurrence of petechiae or spontaneous bleeding. buy viagra online in usa Under this reduced dosing regimen, the disease has remained in remission for >1 year. buy generic viagra Discussion: due to the low prevalence of iph, only limited data document the safety and efficacy of immunosuppressive therapy in treating this disease. buying generic viagra online Although our patient showed a good response to low-dose cyclophosphamide, he developed thrombocytopenia with its use. The mechanism is unclear, but it may be similar to that of high-dose cyclophosphamide-induced myelosuppression. Due to the development of thrombocytopenia, the use of cyclophosphamide was maintained under a reduced dosing regimen. The benefit of long-term immunosuppressive therapy is controversial, and more clinical evidence is required to support its continued usage. Buy viagra online cheap Conclusions: long-term, low-dose cyclophosphamide is effective in treating childhood iph, but caution should be exercised due to the possible development of thrombocytopenia. Periodic monitoring of the platelet count in long-term treatment is recommended. buy viagra canada Cyclophosphamide, low-dose idiopathic pulmonary hemosiderosis pediatrics thrombocytopenia â« previous | next article â» table of contents this article doi: 1. Buy viagra online without prescription Best site to buy viagra Phone: (301) 333-6200 Toll Free: (800) 324-6340 Email: cranes@craneserviceco.com
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